Click here to download adult dosage chart. Acetaminophen. ACETAMINOPHEN REGULAR STRENGTH for example Tylenol® Regular Strength 325 mg per pill. DOSE &. FREQUENCY. 2 pills every 4 to 6 hours while symptoms last. DAILY LIMIT. Do not take more than 10 pills in 24 hours, unless directed by a doctor. In acetaminophen products available over the counter, each pill may contain 325, 500, or 650 milligrams of the drug. Be extra cautious when taking 500 or 650 milligram pills. Stick to recommended doses. When taking acetaminophen, don't be tempted to add a little extra to the recommended dose. A small-bodied person should stay on the low end of.